Fc gamma RIIIA/CD16a (F176)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P08637-1 |
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Species | Human |
Sequence | Gly17-Gln208(F176) |
Purity | > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
Endotoxin Level | Less than 1EU per µg by the LAL method. |
Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized Fc gamma RIIIA/CD16a (F176), His & Avi, Human at 2 µg/ml (100 µl/well) on the plate can bind Anti-Fc gamma RIIIA Antibody, hFc Tag. Test result was comparable to standard batch. |
Expression System | HEK293 |
Theoretical Molecular Weight | 24.7 kDa |
Formulation | Lyophilized from a 0.22 µm filtered solution in PBS, (pH 7.4). |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 µg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background | Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
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