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Fc gamma RIII/CD16
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q5D5I8 |
|---|---|
| Species | Mouse |
| Sequence | Leu32-Thr215 |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Endotoxin Level | Less than 1EU per µg by the LAL method. |
| Biological Activity | OKT3 captured on CM5 Chip via Protein A can bind Fc gamma RIII/CD16[Biotin], His & Avi, Mouse in SPR assay (Biacore T200). Test result was comparable to standard batch. |
| Expression System | HEK293 |
| Theoretical Molecular Weight | 23.97 kDa |
| Formulation | Lyophilized from a 0.22 µm filtered solution in PBS, (pH 7.4). |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 µg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background | Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set. |
|---|
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
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Cat# PVGS1926
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