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CD8 alpha/CD8A
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P01732-1 |
|---|---|
| Species | Human |
| Sequence | Ser22-Asp182 |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Endotoxin Level | Less than 1EU per µg by the LAL method. |
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized CD8 alpha/CD8A[Biotin], His & Avi, Human at 0.5 µg/ml (100 µl/well) on the streptavidin precoated plate (5 µg/ml) can bind Anti-CD8 Antibody, hFc Tag. Test result was comparable to standard batch. |
| Expression System | HEK293 |
| Theoretical Molecular Weight | 20.5 kDa |
| Formulation | Lyophilized from a 0.22 µm filtered solution in PBS, (pH 7.4). |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 µg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background | CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known. |
|---|
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
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Cat# PVGS1923
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