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Fc gamma RIIIB/CD16b (NA1)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | AAA35881.1 |
|---|---|
| Species | Human |
| Sequence | Gly17-Ser200 |
| Purity | > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
| Endotoxin Level | Less than 1EU per µg by the LAL method. |
| Biological Activity | Fc gamma RIIIB/CD16b (NA1)[Biotin], His & Avi, Human captured on CM5 Chip via antihis antibody can bind Rituximab in SPR assay (Biacore T200). Test result was comparable to standard batch. |
| Expression System | HEK293 |
| Theoretical Molecular Weight | 23.81 kDa |
| Formulation | Lyophilized from a 0.22 µm filtered solution in PBS, (pH 7.4). |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 µg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background | Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. |
|---|
Research Areas
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
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Cat# PVGS1916
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