VEGF R1/FLT-1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P17948-1 |
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Species | Human |
Sequence | Ser27-Asn756 |
Purity | > 95% as determined by Bis-Tris PAGE |
Endotoxin Level | Less than 1EU per µg by the LAL method. |
Biological Activity | Immobilized VEGF R1/FLT-1, His&Avi, Human (Cat.No.: Z03964) 2 µg/ml (100 µl/well) on the plate can bind Biotinylated Human VEGF121, His Tag |
Expression System | HEK293 |
Theoretical Molecular Weight | 85.1 kDa |
Formulation | Lyophilized from a 0.22 µm filtered solution in PBS, (pH 7.4). |
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 µg/ml. |
Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background | Vascular endothelial growth factor receptor 1(VEGFR1), also known as Flt-1, is a type I transmembrane glycoprotein of receptor tyrosine kinases (RTKs) family. VEGFR1 acts as a cell-surface receptor for VEGFA, VEGFB and PGF. It plays an important role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration and cancer cell invasion. |
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