VEGF R3/FLT4
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P35916-1 |
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Species | Human |
Sequence | Tyr25-Ile776 |
Purity | > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
Endotoxin Level | Less than 1EU per µg by the LAL method. |
Biological Activity | Immobilized Human VEGF-C, His Tag at 5 µg/ml (100 µl/Well) on the plate can bind VEGF R3/FLT4[Biotin], His&Avi, Human (Cat.No.: Z03971) |
Expression System | HEK293 |
Theoretical Molecular Weight | 87.4 kDa |
Formulation | Lyophilized from a 0.22 µm filtered solution in PBS, (pH 7.4). |
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 µg/ml. |
Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Target Background | Vascular endothelial growth factor receptor 3 (VEGFR3) is one kind of tyrosine-protein kinase. VEGFR3 acts as a cell-surface receptor for VEGFC and VEGFD. It is a key regulator of lymphatic system development and establishment. VEGFR3 plays important roles in angiogenesis. It is also up-regulated in the endothelium of blood vessels in breast cancer and various other tumors. |
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