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FGF-basic
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | A0A287BGK8 |
|---|---|
| Species | Porcine |
| Sequence | Pro171-Ser316 |
| Purity | ≥ 95% as analyzed by SDS-PAGE |
| Endotoxin Level | < 0.2 EU/ µg of protein by gel clotting method |
| Biological Activity | ED50 < 1.0 ng/ml, measured by a cell proliferation assay using BALB/3T3 cells, corresponding to a specific activity of > 1.0 ×106 units/mg. |
| Expression System | E. coli |
| Theoretical Molecular Weight | 16.4 kDa |
| Formulation | Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4 |
| Reconstitution | Before opening, centrifuge the vial briefly to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O up to 100 µg/ml |
| Storage & Stability | Upon receiving, this product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable up to 1 week at 4 °C or up to 3 months at -20 °C or below. Avoid repeated freeze-thaw cycles. |
| Target Background | Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine. FGF-basic is produced by fibroblasts, and vascular cells. It regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. |
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Research Areas
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Cat# PVGS1757
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