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VEGFR2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P35968-1 |
|---|---|
| Species | Human |
| Sequence | Ala20-Glu764 |
| Purity | > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
| Endotoxin Level | Less than 1 EU per µg by the LAL method. |
| Biological Activity | Immobilized VEGFR2, Avi & His, Human (Cat.No.: Z03811) at 0.5 µg/ml can bind AntiVEGFR2 Antibody. |
| Expression System | HEK293 |
| Theoretical Molecular Weight | 86.2 kDa |
| Formulation | Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 µg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability | Upon receiving, the lyophilized product remains stable up to 6 months at -20 °C or below as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Target Background | The kinase insert domain receptor (KDR), also known as vascular endothelial growth factor receptor 2 (VEGFR-2), is a type IV receptor tyrosine kinase that plays a crucial role in various biological processes, including embryonic vasculature development, angiogenesis regulation, cell survival, migration, macrophage function, chemotaxis, and cancer cell invasion. It acts as a cell-surface receptor for VEGFA, VEGFB, and PGF. The human gene encoding KDR is also known as CD309 and Flk1 (Fetal Liver Kinase 1). VEGFR2 is a key regulator of angiogenesis. |
|---|
Research Areas
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Cat# PVGS1693
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