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EGF

     
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Product Information
Primary Accession Q00968
Species Porcine
Sequence Arg969-Arg1022
Purity ≥ 95% as analyzed by SDS-PAGE
Endotoxin Level < 0.2 EU/ µg of protein by gel clotting method
Biological Activity ED50 < 0.2 ng/ml, measured by a cell proliferation assay using BALB/3T3 cells, corresponding to a specific activity of > 5.0 × 106 units/mg.
Expression System E.coli
Theoretical Molecular Weight 6.3 kDa
Formulation Lyophilized from a 0.2 µm filtered solution in 50mM Tris, pH8.0
Reconstitution Before opening, centrifuge the vial briefly to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2 O up to 100 µg/ml
Storage & Stability Upon receiving, the lyophilized product remains stable for up to 6 months at lower than -70 °C. Upon reconstitution, the product is stable for up to 1 week at 4 °C or up to 3 months at -20 °C. Avoid repeated freeze-thaw cycles by making single-use aliquots before the solution is stored at -20 °C.
Additional Information
Gene ID 397083
Other Names Pro-epidermal growth factor, EGF, Epidermal growth factor, EGF
Target Background EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
Protein Information
Name EGF
Function EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein.
Research Areas
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Cat# PVGS1689
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