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CCL23, Human

     
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Product Information
Primary Accession AAC63327
Species Human
Sequence MLWRRKIGPQ MTLSHAAGFH ATSADCCISY TPRSIPCSLL ESYFETNSEC SKPGVIFLTK KGRRFCANPS DKQVQVCVRM LKLDTRIKTR KN
Purity > 98% as analyzed by SDS-PAGE.
Endotoxin Level < 0.2 EU/ µg, determined by LAL method.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 µg/ml.
Additional Information
Target Background Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family that is also known as Macrophage inflammatory protein 3 (MIP-3) and Myeloid progenitor inhibitory factor 1 (MPIF-1). CCL23 is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta.CCL23 is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. CCL23 is a ligand for the chemokine receptor CCR1.
Recombinant human Ck beta 8‑1/CCL23 produced in CHO cells is a single polypeptide chain containing 92 amino acids. A fully biologically active molecule, rhCk beta 8‑1/CCL23 has a molecular mass of 10.5 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at .
Protein Information
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Cat# PVGS1402
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