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S100-A6
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | NP_055439.1 |
|---|---|
| Species | Human |
| Sequence | MHHHHHHMAC PLDQAIGLLV AIFHKYSGRE GDKHTLSKKE LKELIQKELT IGSKLQDAEI ARLMEDLDRN KDQEVNFQEY VTFLGALALI YNEALKG |
| Purity | > 95% as analyzed by SDS-PAGE. |
| Endotoxin Level | < 1 EU/ µg, determined by LAL method. |
| Formulation | Lyophilized after extensive dialysis against 50mM Tris-HCl, 100mM NaCI, 0.5mM PMSF, 1mM TCEP, pH8.0. |
| Reconstitution | Reconstituted in ddH2O at 200 µg/ml. |
| Target Background | S100 calcium-binding protein A6 (S100A6) is a small calcium binding protein with 2 EF-hand structures and belongs to the S100 family. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 proteins include at least 25 members which are located as a cluster on chromosome 1q21. S100A6 protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. Recombinant S100 calcium-binding protein A6 (S100A6) with His tag produced in E. coli is a single chain containing 97 amino acids with molecular mass of 11.1 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at . |
|---|
Research Areas
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Cat# PVGS1303
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