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Protein S100-A4
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | NP_002952.1 |
|---|---|
| Species | Human |
| Sequence | MACPLEKALD VMVSTFHKYS GKEGDKFKLN KSELKELLTR ELPSFLGKRT DEAAFQKLMS NLDSNRDNEV DFQEYCVFLS CIAMMCNEFF EGFPDKQPRK K |
| Purity | > 90% as analyzed by SDS-PAGE. |
| Endotoxin Level | < 1 EU/ µg, determined by LAL method. |
| Formulation | Lyophilized after extensive dialysis against 20 mM Tris-HCl, 100 mM NaCl , pH8.0. |
| Reconstitution | Reconstituted in ddH2O at 200 µg/ml. |
| Target Background | S100 calcium-binding protein A4 (S100A4) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A4 promotes metastasis in several experimental animal models, and S100A4 protein expression is associated with differential patient outcome in a number of tumor types. S100A4 is localized in the nucleus, cytoplasm, and extracellular space and possesses a wide range of biological functions such as regulation of angiogenesis, cell survival, motility, and invasion. Recombinant S100 calcium-binding protein A4 (S100A4) produced in E. coli is a single chain containing 101 amino acids with molecular mass of 11.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at . |
|---|
Research Areas
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Cat# PVGS1279
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