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Eotaxin-2/CCL24

     
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Product Information
Primary Accession Q5PPP2
Species Rat
Sequence Pro23-Val119, expressed with an N-terminal Met
Purity > 96% as analyzed by SDS-PAGE
> 96% as analyzed by HPLC
Endotoxin Level < 1 EU/ µg of protein by LAL method
Biological Activity Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration of 50.0-250.0 ng/ml.
Expression System E. coli
Theoretical Molecular Weight 10.5 kDa
Formulation Lyophilized from a 0.2 µm filtered solution in 2 × PBS, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.
Additional Information
Target Background Eotaxin-2/CCL24, also named MPIF-2 and Ckβ6, is a novel CC chemokine recently identified. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the mouse homolog, without C-terminal truncation).
Protein Information
Research Areas
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Cat# PVGS1198
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