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C7 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P10643 |
|---|---|
| Clone Names | 90805016 |
| Gene ID | 730 |
|---|---|
| Other Names | Complement component C7, C7 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9262c was selected from the Center region of human C7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | C7 |
|---|---|
| Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection.
References
Davila,S., et.al., Genes Immun. 11 (3), 232-238 (2010)Kuijpers,T.W., et.al., Mol. Immunol. 47 (4), 671-677 (2010)Wheeler,H.E., et.al., PLoS Genet. 5 (10), E1000685 (2009)
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