PPEF1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O14829 |
---|---|
Clone Names | 4021328 |
Gene ID | 5475 |
---|---|
Other Names | Serine/threonine-protein phosphatase with EF-hands 1, PPEF-1, Protein phosphatase with EF calcium-binding domain, PPEF, Serine/threonine-protein phosphatase 7, PP7, PPEF1, PPEF, PPP7C |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8474a was selected from the N-term region of human PPEF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PPEF1 |
---|---|
Synonyms | PPEF, PPP7C |
Function | May have a role in the recovery or adaptation response of photoreceptors. May have a role in development. |
Tissue Location | Detected in retina and retinal derived Y-79 retinoblastoma cells. Also found in fetal brain |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
PPEF1 is a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. The protein shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) protein.
References
Kutuzov, M.A., et al., Biochem. Biophys. Res. Commun. 293(3):1047-1052 (2002).Ramulu, P., et al., Mol. Cell. Biol. 21(24):8605-8614 (2001).Herzig, S., et al., Physiol. Rev. 80(1):173-210 (2000).Huang, X., et al., J. Biol. Chem. 273(3):1462-1468 (1998).Sherman, P.M., et al., Proc. Natl. Acad. Sci. U.S.A. 94(21):11639-11644 (1997).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.