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NTF5 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P34130 |
|---|---|
| Clone Names | 71211145 |
| Gene ID | 4909 |
|---|---|
| Other Names | Neurotrophin-4, NT-4, Neurotrophin-5, NT-5, Neutrophic factor 4, NTF4, NTF5 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7765b was selected from the C-term region of human NTF5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NTF4 |
|---|---|
| Synonyms | NTF5 |
| Function | Target-derived survival factor for peripheral sensory sympathetic neurons (PubMed:1742028). May promote ameloblast differentiation and subsequent reduction in proliferation of ameloblasts (By similarity). |
| Cellular Location | Secreted. |
| Tissue Location | Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
NTF5 is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
References
Truzzi,F., J. Invest. Dermatol. 128 (8), 2031-2040 (2008)Harel,S., Mol. Hum. Reprod. 12 (6), 357-365 (2006)
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