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DLG3 (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q92796 |
|---|---|
| Clone Names | 100617316 |
| Gene ID | 1741 |
|---|---|
| Other Names | Disks large homolog 3, Neuroendocrine-DLG, Synapse-associated protein 102, SAP-102, SAP102, XLMR, DLG3, KIAA1232 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DLG3 |
|---|---|
| Synonyms | KIAA1232 |
| Function | Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the membrane-associatedguanylate kinase protein family. The encoded protein may play arole in clustering of NMDA receptors at excitatory synapses. It mayalso negatively regulate cell proliferation through interactionwith the C-terminal region of the adenomatosis polyposis coli tumorsuppressor protein. Mutations in this gene have been associatedwith X-linked mental retardation. Alternatively spliced transcriptvariants have been described.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :Zanni, G., et al. Neurogenetics 11(2):251-255(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Gill, M.B., et al. J. Biol. Chem. 284(21):14503-14512(2009)Rikova, K., et al. Cell 131(6):1190-1203(2007)
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