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EHD4 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H223 |
|---|---|
| Clone Names | 110617222 |
| Gene ID | 30844 |
|---|---|
| Other Names | EH domain-containing protein 4, Hepatocellular carcinoma-associated protein 10/11, PAST homolog 4, EHD4, HCA10, HCA11, PAST4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | EHD4 (HGNC:3245) |
|---|---|
| Function | ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport (PubMed:17233914, PubMed:18331452). During sprouting angiogenesis, in complex with PACSIN2 and MICALL1, forms recycling endosome-like tubular structure at asymmetric adherens junctions to control CDH5 trafficking (By similarity). |
| Cellular Location | Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane {ECO:0000250|UniProtKB:Q9EQP2}; Peripheral membrane protein; Cytoplasmic side. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q9EQP2} |
| Tissue Location | Highly expressed in pancreas and heart. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
EHD4 plays a role in early endosomal transport.
References
Gudmundsson, H., et al. Circ. Res. 107(1):84-95(2010)Sharma, M., et al. Traffic 9(6):995-1018(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Kuo, H.J., et al. J. Biol. Chem. 276(46):43103-43110(2001)
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