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CCS Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O14618 |
|---|---|
| Clone Names | 100430356 |
| Gene ID | 9973 |
|---|---|
| Other Names | Copper chaperone for superoxide dismutase, Superoxide dismutase copper chaperone, CCS |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP14113c was selected from the Center region of CCS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CCS (HGNC:1613) |
|---|---|
| Function | Delivers copper to copper zinc superoxide dismutase (SOD1). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Copper chaperone for superoxide dismutase specificallydelivers Cu to copper/zinc superoxide dismutase and may activatecopper/zinc superoxide dismutase through direct insertion of the Cucofactor.
References
Brady, G.F., et al. Mol. Cell. Biol. 30(8):1923-1936(2010)Winkler, D.D., et al. Biochemistry 48(15):3436-3447(2009)Barry, A.N., et al. Biochemistry 47(49):13074-13083(2008)Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)Furukawa, Y., et al. J. Biol. Chem. 283(35):24167-24176(2008)
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