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NEUROD6 Antibody (N-term ) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96NK8 |
|---|---|
| Clone Names | 100416070 |
| Gene ID | 63974 |
|---|---|
| Other Names | Neurogenic differentiation factor 6, NeuroD6, Class A basic helix-loop-helix protein 2, bHLHa2, Protein atonal homolog 2, NEUROD6, ATOH2, BHLHA2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13481a was selected from the N-term region of NEUROD6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NEUROD6 |
|---|---|
| Synonyms | ATOH2, BHLHA2 |
| Function | Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
NEUROD6 is a member of the NEUROD (NEUROD1; MIM 601724)family of basic helix-loop-helix (bHLH) transcription factors (Guoet al., 2002 [PubMed 12357074]).
References
Ribases, M., et al. Biol. Psychiatry 66(10):926-934(2009)Satou, W., et al. Exp. Gerontol. 39(2):173-179(2004)Guo, L., et al. J. Genet. 81(1):13-17(2002)Dintilhac, A., et al. J. Biol. Chem. 277(9):7021-7028(2002)
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