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MGAT4C Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9UBM8 |
|---|---|
| Clone Names | 100324002 |
| Gene ID | 25834 |
|---|---|
| Other Names | Alpha-1, 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C, N-acetylglucosaminyltransferase IV homolog, hGnT-IV-H, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc, GlcNAc-T IVc, GnT-IVc, N-acetylglucosaminyltransferase IVc, UDP-N-acetylglucosamine: alpha-1, 3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase IVc, MGAT4C |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MGAT4C |
|---|---|
| Function | Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas |
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Provided below are standard protocols that you may find useful for product applications.
Background
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri-and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity).
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :Trynka, G., et al. Gut 58(8):1078-1083(2009)Furukawa, T., et al. J. Hum. Genet. 44(6):397-401(1999)Thomas, B.A. Br. J. Dermatol. 80 (6), 413 (1968) :
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