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DEGS2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6QHC5 |
|---|---|
| Other Accession | NP_996801.2 |
| Clone Names | 100111072 |
| Gene ID | 123099 |
|---|---|
| Other Names | Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2, 1---, 114--, Degenerative spermatocyte homolog 2, DEGS2 (HGNC:20113), C14orf66 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DEGS2 (HGNC:20113) |
|---|---|
| Synonyms | C14orf66 |
| Function | Bifunctional enzyme which acts both as a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8R2F2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8R2F2} |
| Tissue Location | Highly expressed in skin, intestine and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DEGS2 encodes a bifunctional enzyme that is involvedin the biosynthesis of phytosphingolipids in human skin and inother phytosphingolipid-containing tissues. This enzyme can act asa sphingolipid delta(4)-desaturase, and also as a sphingolipidC4-hydroxylase.
References
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Mizutani, Y., et al. FEBS Lett. 563 (1-3), 93-97 (2004) :
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