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FGF7 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P21781 |
|---|---|
| Other Accession | NP_002000.1 |
| Clone Names | 91009101 |
| Gene ID | 2252 |
|---|---|
| Other Names | Fibroblast growth factor 7, FGF-7, Heparin-binding growth factor 7, HBGF-7, Keratinocyte growth factor, FGF7, KGF |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FGF7 |
|---|---|
| Synonyms | KGF |
| Function | Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. |
| Cellular Location | Secreted. |
| Tissue Location | Epithelial cell. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of thefibroblast growth factor (FGF) family. FGF family members possessbroad mitogenic and cell survival activities, and are involved in avariety of biological processes, including embryonic development,cell growth, morphogenesis, tissue repair, tumor growth andinvasion. This protein is a potent epithelial cell-specific growthfactor, whose mitogenic activity is predominantly exhibited inkeratinocytes but not in fibroblasts and endothelial cells. Studiesof mouse and rat homologs of this gene implicated roles inmorphogenesis of epithelium, reepithelialization of wounds, hairdevelopment and early lung organogenesis.
References
Lin, C.B., et al. J. Dermatol. Sci. 59(2):91-97(2010)Bando, M., et al. Immunol. Cell Biol. 88(3):328-333(2010)Wang, X., et al. Biomaterials 31(9):2542-2548(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Aguilar, S., et al. PLoS ONE 4 (11), E8013 (2009) :
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