Zebrafish hey2 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9I9L0 |
Reactivity | Zebrafish |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Clone/Animal Names | RB53204 |
Calculated MW | 34329 Da |
Antigen Region | 224-260 aa |
Gene ID | 58146 |
---|---|
Other Names | Hairy/enhancer-of-split related with YRPW motif protein 2, Protein gridlock, hey2, grl |
Target/Specificity | This Zebrafish hey2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 224-260 amino acids from the C-terminal region of Zebrafish hey2. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Zebrafish hey2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | hey2 |
---|---|
Synonyms | grl |
Function | Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation.
References
Zhong T.P.,et al.Science 287:1820-1824(2000).
Zhong T.P.,et al.Nature 414:216-220(2001).
Winkler C.,et al.Dev. Genes Evol. 213:541-553(2003).
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