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DANRE mao Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - DANRE mao Antibody (Center) Azb10032a
    DANRE mao Antibody (Center) (Cat. #Azb10032a) western blot analysis in zebra fish brain tissue lysates (35ug/lane).This demonstrates the DANRE mao antibody detected the DANRE mao protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6NSN2
Reactivity Zebrafish
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 58765 Da
Antigen Region 332-364 aa
Additional Information
Gene ID 404730
Other Names Amine oxidase [flavin-containing], Monoamine oxidase, MAO, Z-MAO, AOF
Target/Specificity This DANRE mao antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-364 amino acids from the Central region of DANRE mao.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDANRE mao Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name mao {ECO:0000312|EMBL:AAH70013.1, ECO:0000312|ZFIN:ZDB-GENE-040329-3}
Function Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:15621520, PubMed:16917825). Preferentially oxidizes serotonin and tyramine (PubMed:15621520, PubMed:16917825). Also catalyzes the oxidative deamination of kynuramine to 3-(2- aminophenyl)-3-oxopropanal that can spontaneously condense to 4- hydroxyquinoline (By similarity).
Cellular Location Mitochondrion outer membrane {ECO:0000250|UniProtKB:P21396}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:P21396}; Cytoplasmic side {ECO:0000250|UniProtKB:P21396}
Tissue Location Strongest expression in brain and intestine, followed by liver, heart and gill. Little expression in spleen, eye or muscle. In brain, highest activity in noradrenergic and serotonergic cell groups and those of the habenulointerpeduncular pathway; moderate levels in dopaminergic cell clusters.
Research Areas
Citations (0)
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Background

Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Oxidizes both 5-hydroxytryptamine (5-HT) and beta-phenylethylamine (PEA).

References

Setini A., et al. Comp. Biochem. Physiol. 140B:153-161(2005).
Anichtchik O., et al. J. Comp. Neurol. 498:593-610(2006).

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$ 365.00
$ 140.00
Cat# Azb10032a
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