DANRE heg Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q6R8J2 |
Reactivity | Zebrafish |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 105529 Da |
Antigen Region | 691-717 aa |
Other Names | Protein HEG, Heart of glass, heg |
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Target/Specificity | This DANRE heg antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 691-717 amino acids from the C-terminal region of DANRE heg. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DANRE heg Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | heg |
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Function | Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. |
Cellular Location | [Isoform 1]: Cell membrane; Single- pass type I membrane protein. Cell junction [Isoform 3]: Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions.
References
Mably J.D., et al. Curr. Biol. 13:2138-2147(2003).
Kleaveland B., et al. Nat. Med. 15:169-176(2009).
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