DANRE pax2a Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q90268 |
Reactivity | Zebrafish |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 44099 Da |
Antigen Region | 258-284 aa |
Gene ID | 30425 |
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Other Names | Paired box protein Pax-2a, No isthmus protein, Pax[Zf-b], pax2a, noi, pax21, paxzf-b |
Target/Specificity | This DANRE pax2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-284 amino acids from the Central region of DANRE pax2a. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DANRE pax2a Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | pax2a |
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Synonyms | noi, pax2.1, paxzf-b |
Function | Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. |
Cellular Location | Nucleus. |
Tissue Location | Expressed during embryogenesis in the kidney, optic stalk, midbrain, otic vesicle and a row of cells along the spinal cord and the hindbrain |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation.
References
Krauss S., et al. Development 113:1193-1206(1991).
Lun K., et al. Development 125:3049-3062(1998).
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