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Anti-Trastuzumab monoclonal antibody (1402CT432.13.33.67)

Purified Mouse Monoclonal Antibody (Mab)

     
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  • sELISA - Anti-Trastuzumab monoclonal antibody (1402CT432.13.33.67) AW5687-U100
    Plate was coated with Herceptin and Human IgG1,κ at 1.25 µg/ml in PBS, and then incubated with anti-Herceptin monoclonal antibody (1402CT432.13.33.67) from 0.004 µg/ml to 2 µg/ml. The secondary antibody, HRP conjugated goat anti-mouse antibody,were used at 1:10000 dilution.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
sELISA
Host Mouse
Clonality Monoclonal
Isotype IgG2a,κ
Antigen Source A recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein. Produced in CHO cell culture. In December 2017, FDA approved Ogivri (trastuzumab-dkst) as a biosimilar to Herceptin (trastuzumab) for the treatment of patients with breast or metastatic stomach cancer (gastric or gastroesophageal junction adenocarcinoma) whose tumors overexpress the HER2 gene (HER2+). It displays biosimilar properties as Herceptin according to clinical data. While Ogivri is the first biosimilar approved in the U.S. for the treatment of breast cancer or stomach cancer, it is the second biosimilar approved in the U.S. for the treatment of cancer.
Additional Information
Other Names Anti-Herceptin monoclonal antibody
Target/Specificity Mouse monoclonal antibody raised against Trastuzumab.
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAnti-Trastuzumab monoclonal antibody (1402CT432.13.33.67) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
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$ 380.00
Cat# AW5687-U100
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