EEF1E1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IF, FC, WB |
---|---|
Primary Accession | O43324 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | H=20,16;M=20 KDa |
Isotype | IgG2b,κ |
Antigen Source | HUMAN |
Gene ID | 9521 |
---|---|
Antigen Region | 1-112 aa |
Other Names | Eukaryotic translation elongation factor 1 epsilon-1, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3, Elongation factor p18, Multisynthase complex auxiliary component p18, EEF1E1, AIMP3, P18 |
Dilution | IF~~1:25 WB~~1:2000 FC~~1:25 |
Target/Specificity | This EEF1E1 antibody is generated from a mouse immunized with a recombinant protein of human EEF1E1. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | EEF1E1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EEF1E1 |
---|---|
Synonyms | AIMP3, P18 {ECO:0000303|PubMed:15680327} |
Function | Positive modulator of ATM response to DNA damage. |
Cellular Location | Cytoplasm. Cytoplasm, cytosol. Nucleus. Note=Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage |
Tissue Location | Down-regulated in various cancer tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Positive modulator of ATM response to DNA damage.
References
Motegi H.,et al.Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
Mao M.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Bienvenut W.V.,et al.Submitted (DEC-2008) to UniProtKB.
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