Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
RAE1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P78406 |
| Other Accession | Q5E9A4, Q4R6D2, Q8C570, Q3SWS8, A5GFN6, Q5RF99 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Monkey, Rat, Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=41;M=41;R=41 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 8480 |
|---|---|
| Antigen Region | 128-162 aa |
| Other Names | mRNA export factor, Rae1 protein homolog, mRNA-associated protein mrnp 41, RAE1, MRNP41 |
| Dilution | WB~~1:2000 |
| Target/Specificity | This RAE1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 128-162 amino acids from the Central region of human RAE1. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RAE1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAE1 |
|---|---|
| Synonyms | MRNP41 |
| Function | Acts as a mRNA export factor involved in nucleocytoplasmic transport (PubMed:20498086, PubMed:33849972). Plays a role in mitotic bipolar spindle formation (PubMed:17172455). May function in attaching cytoplasmic mRNPs to the cytoskeleton both directly or indirectly (PubMed:17172455). |
| Cellular Location | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Nucleus envelope. Note=Recruited from interphase nuclei to spindle MTs during mitosis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.
References
Bharathi A.,et al.Gene 198:251-258(1997).
Kraemer D.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:9119-9124(1997).
Lu L.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
