Zebrafish ak2 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, FC |
---|---|
Primary Accession | Q1L8L9 |
Reactivity | Zebrafish |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | Z=27 KDa |
Isotype | Rabbit IgG |
Antigen Source | HUMAN |
Gene ID | 321793 |
---|---|
Antigen Region | 3~39 aa |
Other Names | Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}, AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}, 2743 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}, ak2 |
Dilution | WB~~1:2000 IHC~~1:25 FC~~1:25 |
Target/Specificity | This Zebrafish ak2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3~39 amino acids from the N-terminal region of Zebrafish ak2. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Zebrafish ak2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ak2 |
---|---|
Function | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. |
Cellular Location | Mitochondrion intermembrane space {ECO:0000255|HAMAP-Rule:MF_03168} |
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Background
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
References
Howe K.,et al.Nature 496:498-503(2013).
Pannicke U.,et al.Nat. Genet. 41:101-105(2009).
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