ETV1 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P50549 |
Other Accession | Q2KIC2, P41164 |
Reactivity | Human, Mouse |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | H=55,53,52,43,48,50;M=55 KDa |
Isotype | Rabbit IgG |
Antigen Source | HUMAN |
Gene ID | 2115 |
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Antigen Region | 434-465 aa |
Other Names | ETS translocation variant 1, Ets-related protein 81, ETV1, ER81 |
Dilution | WB~~0.25 |
Target/Specificity | This ETV1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 434-465 amino acids from human ETV1. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ETV1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ETV1 (HGNC:3490) |
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Function | Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (PubMed:7651741). Required for olfactory dopaminergic neuron differentiation; may directly activate expression of tyrosine hydroxylase (TH) (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}. |
Tissue Location | Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
References
Jeon I.-S.,et al.Oncogene 10:1229-1234(1995).
Monte D.,et al.Oncogene 11:771-779(1995).
Coutte L.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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