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CMA1 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P23946 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=27,15;M=28;R=28 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 1215 |
|---|---|
| Antigen Region | 84-118 aa |
| Other Names | Chymase, Alpha-chymase, Mast cell protease I, CMA1, CYH, CYM |
| Dilution | WB~~1:2000 |
| Target/Specificity | This CMA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 84-118 amino acids from human CMA1. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CMA1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CMA1 |
|---|---|
| Synonyms | CYH, CYM |
| Function | Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
| Cellular Location | Secreted. Cytoplasmic granule. Note=Mast cell granules |
| Tissue Location | Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
References
Caughey G.H.,et al.J. Biol. Chem. 266:12956-12963(1991).
Urata H.,et al.J. Biol. Chem. 266:17173-17179(1991).
Schechter N.M.,et al.J. Immunol. 152:4062-4069(1994).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Heilig R.,et al.Nature 421:601-607(2003).
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