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SLC5A4 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9NY91 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=72 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 6527 |
|---|---|
| Antigen Region | 601-635 aa |
| Other Names | Low affinity sodium-glucose cotransporter, Sodium/glucose cotransporter 3, Na(+)/glucose cotransporter 3, Solute carrier family 5 member 4, SLC5A4, SAAT1, SGLT2 |
| Dilution | WB~~1:1000 |
| Target/Specificity | This SLC5A4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 601-635 amino acids from the C-terminal region of human SLC5A4. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLC5A4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC5A4 {ECO:0000303|PubMed:13130073} |
|---|---|
| Function | Does not function as sodium/D-glucose symporter (PubMed:13130073, PubMed:20421923, PubMed:22766068). However, may function as a D-glucose sensor by generating a D-glucose-induced depolarization which is pH-independent, Na(+)-dependent at neutral pH and probably H(+)-dependent at acidic pH (PubMed:13130073, PubMed:17110502, PubMed:20421923, PubMed:22766068). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in skeletal muscle, where it may localize to the neuromuscular junction (at protein level) (PubMed:13130073) Expressed in small intestine where it may localize to cholinergic neurons of the submucosal plexus and myenteric plexus (at protein level) (PubMed:13130073). Detected in kidney (at protein level) (PubMed:22766068). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Sodium-dependent glucose transporter.
References
Gorboulev V.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Dunham I.,et al.Nature 402:489-495(1999).
Poppe R.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
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