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> home > Products > Primary Antibodies > Antibody Collections > Ribonucleoprotein > SNRPA Antibody (Center)
SNRPA Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P09012 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=31;M=32 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 6626 |
|---|---|
| Antigen Region | 83-111 aa |
| Other Names | U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A, SNRPA |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Target/Specificity | This SNRPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the Central region of human SNRPA. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SNRPA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SNRPA |
|---|---|
| Function | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs. |
| Cellular Location | Nucleus. |
Research Areas
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$ 385.00
Cat# AW5557-U100
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