PECI Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, FC, WB |
---|---|
Primary Accession | O75521 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | H=44,40 KDa |
Isotype | Rabbit IgG |
Antigen Source | HUMAN |
Gene ID | 10455 |
---|---|
Antigen Region | 331-358 aa |
Other Names | Enoyl-CoA delta isomerase 2, mitochondrial, DRS-1, Delta(3), delta(2)-enoyl-CoA isomerase, D3, D2-enoyl-CoA isomerase, Diazepam-binding inhibitor-related protein 1, DBI-related protein 1, Dodecenoyl-CoA isomerase, Hepatocellular carcinoma-associated antigen 88, Peroxisomal 3, 2-trans-enoyl-CoA isomerase, pECI, Renal carcinoma antigen NY-REN-1, ECI2, DRS1, HCA88, PECI |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Target/Specificity | This PECI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-358 amino acids from the C-terminal region of human PECI. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PECI Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ECI2 |
---|---|
Synonyms | DRS1, HCA88, PECI {ECO:0000303|PubMed:10 |
Function | Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates. |
Cellular Location | [Isoform 1]: Mitochondrion {ECO:0000250|UniProtKB:Q5XIC0} |
Tissue Location | Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
PECI is an auxiliary enzyme that catalyzes an isomerization step required for the beta-oxidation of unsaturated fatty acids.
References
Scanlan,M.J., et.al., Int. J. Cancer 83 (4), 456-464 (1999)
Suk,K., et.al., Biochim. Biophys. Acta 1454 (1), 126-131 (1999)
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