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(Mouse) Dpf2 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q61103 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | M=44;H=44,24 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 19708 |
|---|---|
| Antigen Region | 99-133 aa |
| Other Names | Zinc finger protein ubi-d4, Apoptosis response zinc finger protein, BRG1-associated factor 45D, BAF45D, D4, zinc and double PHD fingers family 2, Protein requiem, Dpf2, Baf45d, Req, Ubid4 |
| Dilution | WB~~1:2000 IHC~~1:25 |
| Target/Specificity | This mouse Dpf2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-133 amino acids from the N-terminal region of mouse Dpf2. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | (Mouse) Dpf2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Dpf2 |
|---|---|
| Synonyms | Baf45d, Req, Ubid4 |
| Function | Plays an active role in transcriptional regulation by binding modified histones H3 and H4. Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (By similarity). Might also have a role in the development and maturation of lymphoid cells (PubMed:7961935). Involved in the regulation of non-canonical NF- kappa-B pathway (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q92785}. Cytoplasm {ECO:0000250|UniProtKB:Q92785} |
| Tissue Location | In embryo, highest levels are seen in brain, eyes, thymus and olfactory epithelium in nose, whereas several other tissues, including the musculoskeletal system, show moderate expression. In adult, higher expression in testis, medium in thymus and spleen, lower in certain parts of the brain as the hippocampus. No expression in adult heart, lung, liver, duodenum and kidney |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.
References
Mertsalov I.B.,et al.Mamm. Genome 11:72-74(2000).
Carninci P.,et al.Science 309:1559-1563(2005).
Gabig T.G.,et al.J. Biol. Chem. 269:29515-29519(1994).
Gabig T.G.,et al.Mamm. Genome 9:660-665(1998).
Lessard J.,et al.Neuron 55:201-215(2007).
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