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EXOC3 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O60645 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=87,74,86 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 11336 |
|---|---|
| Antigen Region | 524-557 aa |
| Other Names | Exocyst complex component 3, Exocyst complex component Sec6, EXOC3, SEC6, SEC6L1 |
| Dilution | WB~~1:1000 IHC-P~~1:25 |
| Target/Specificity | This EXOC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 524-557 amino acids from the C-terminal region of human EXOC3. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | EXOC3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EXOC3 |
|---|---|
| Synonyms | SEC6, SEC6L1 |
| Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:O54921}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54921}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54921}. Midbody. Golgi apparatus. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q62825}. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB- dependent (PubMed:18756269). {ECO:0000250|UniProtKB:O54921, ECO:0000269|PubMed:18756269} |
| Tissue Location | Expressed in epididymis (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
References
Li J.,et al.Mol. Cell. Proteomics 9:2517-2528(2010).
Jikuya H.,et al.DNA Res. 10:49-57(2003).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Yu W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
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