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(DANRE) sdhb Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | A5PL98 |
| Other Accession | P21913, Q007T0, Q9CQA3, P21912, Q9YHT2, Q3T189 |
| Reactivity | Human, Mouse, Rat, Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | Z=32;H=32;M=32;R=32 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 562149 |
|---|---|
| Antigen Region | 147-182 aa |
| Other Names | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip, sdhb |
| Dilution | WB~~1:1000 |
| Target/Specificity | This (DANRE) sdhb antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 147-182 amino acids from the region of (DANRE) sdhb. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | (DANRE) sdhb Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | sdhb |
|---|---|
| Function | Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). SDH also oxidizes malate to the non- canonical enol form of oxaloacetate, enol-oxaloacetate. Enol- oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity). |
| Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9YHT2}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9YHT2}; Matrix side {ECO:0000250|UniProtKB:Q9YHT2} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity).
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