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MTTP Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - MTTP Antibody (C-term) AW5427-U100
    All lanes : Anti-MTTP Antibody (C-term) at 1:1000 dilution Lane 1: HepG2 whole cell lysates Lane 2: human liver lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 99 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • FC - MTTP Antibody (C-term) AW5427-U100
    Flow cytometric analysis of Hela cells using MTTP Antibody (C-term)(green, Cat#AW5427) compared to an isotype control of rabbit IgG(blue). AW5427 was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC
Primary Accession P55157
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=99 KDa
Isotype Rabbit IgG
Antigen Source HUMAN
Additional Information
Gene ID 4547
Antigen Region 878-911 aa
Other Names Microsomal triglyceride transfer protein large subunit, MTTP, MTP
Dilution WB~~1:1000
FC~~1:25
Target/Specificity This MTTP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 878-911 amino acids from the C-terminal region of human MTTP.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMTTP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTTP
Synonyms MTP
Function Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:15897609, PubMed:16478722, PubMed:22236406, PubMed:23475612, PubMed:25108285, PubMed:26224785, PubMed:8876250, PubMed:8939939). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:16478722, PubMed:23475612, PubMed:26224785, PubMed:8876250, PubMed:8939939). May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (By similarity).
Cellular Location Endoplasmic reticulum. Golgi apparatus. Note=Colocalizes with P4HB/PDI in the endoplasmic reticulum (PubMed:23475612, PubMed:26224785)
Tissue Location Liver and small intestine. Also found in ovary, testis and kidney.
Citations (0)
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Background

Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B.

References

Shoulders C.C.,et al.Hum. Mol. Genet. 2:2109-2116(1993).
Sharp D.,et al.Nature 365:65-69(1993).
Sharp D.,et al.Biochemistry 33:9057-9061(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hagan D.L.,et al.J. Biol. Chem. 269:28737-28744(1994).

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$ 370.00
Cat# AW5427-U100
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