SEMA4F Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | O95754 |
Other Accession | Q9Z143, Q9Z123 |
Reactivity | Human, Rat |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | H=84,66;M=84;R=84 KDa |
Isotype | Rabbit IgG |
Antigen Source | HUMAN |
Gene ID | 10505 |
---|---|
Antigen Region | 695-709 aa |
Other Names | Semaphorin-4F, Semaphorin-M, Sema M, Semaphorin-W, Sema W, SEMA4F, SEMAM, SEMAW |
Dilution | WB~~1:1000 |
Target/Specificity | This SEMA4F antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 695-709 amino acids from the C-terminal region of human SEMA4F. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SEMA4F Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SEMA4F |
---|---|
Synonyms | SEMAM, SEMAW |
Function | Probable cell surface receptor that regulates oligodendroglial precursor cell migration (By similarity). Might also regulate differentiation of oligodendroglial precursor cells (By similarity). Has growth cone collapse activity against retinal ganglion-cell axons (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Postsynaptic density {ECO:0000250|UniProtKB:Q9Z143}. Perikaryon {ECO:0000250|UniProtKB:Q9Z123}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9Z123}. Note=Colocalizes with DLG4 at synapses {ECO:0000250|UniProtKB:Q9Z123} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Has growth cone collapse activity against retinal ganglion-cell axons (By similarity).
References
Encinas J.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:2491-2496(1999).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Hillier L.W.,et al.Nature 434:724-731(2005).
Jang W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
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