ACTN2 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | P35609 |
Other Accession | Q9JI91, P20111, Q3ZC55 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | H=104;M=104 KDa |
Isotype | Rabbit IgG |
Antigen Source | HUMAN |
Gene ID | 88 |
---|---|
Antigen Region | 352-386 aa |
Other Names | Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein, ACTN2 |
Dilution | WB~~1:1000 |
Target/Specificity | This ACTN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 352-386 amino acids from the Central region of human ACTN2. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ACTN2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ACTN2 |
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Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
Cellular Location | Cytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle |
Tissue Location | Expressed in both skeletal and cardiac muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
References
Beggs A.H.,et al.J. Biol. Chem. 267:9281-9288(1992).
Tiso N.,et al.Biochem. Biophys. Res. Commun. 265:256-259(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Faulkner G.,et al.J. Cell Biol. 146:465-475(1999).
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