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HMGA2 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P52926 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=12, 9, 10, 11;M=12 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 8091 |
|---|---|
| Antigen Region | 15-49 aa |
| Other Names | High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC |
| Dilution | WB~~1:1000 |
| Target/Specificity | This HMGA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 15-49 amino acids from the N-terminal region of human HMGA2. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HMGA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HMGA2 |
|---|---|
| Synonyms | HMGIC |
| Function | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (PubMed:28796236). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.
References
Patel U.A.,et al.Biochem. Biophys. Res. Commun. 201:63-70(1994).
Schoenmakers E.F.P.M.,et al.Nat. Genet. 10:436-444(1995).
Chau K.-Y.,et al.Nucleic Acids Res. 23:4262-4266(1995).
Ashar H.R.,et al.Genomics 31:207-214(1996).
Hauke S.,et al.Biochim. Biophys. Acta 1729:24-31(2005).
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