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DECR1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q16698 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=36;M=36;Rat=36 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 1666 |
|---|---|
| Antigen Region | 241-274 aa |
| Other Names | 4-dienoyl-CoA reductase, mitochondrial, 4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase [NADPH], DECR1, DECR |
| Dilution | WB~~1:1000 |
| Target/Specificity | This DECR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 241-274 amino acids from the Central region of human DECR1. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DECR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DECR1 |
|---|---|
| Synonyms | DECR, SDR18C1 |
| Function | Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. |
| Cellular Location | Mitochondrion. |
| Tissue Location | Heart = liver = pancreas > kidney >> skeletal muscle = lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA.
References
Koivuranta K.T.,et al.Biochem. J. 304:787-792(1994).
Ding J.H.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
Helander H.M.,et al.Genomics 46:112-119(1997).
Nusbaum C.,et al.Nature 439:331-335(2006).
Choudhary C.,et al.Science 325:834-840(2009).
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