STIP1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, FC |
---|---|
Primary Accession | P31948 |
Other Accession | O35814, Q60864, O54981, Q3ZBZ8 |
Reactivity | Human |
Predicted | Bovine, Hamster, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | H=63;M=63;Rat=63 KDa |
Isotype | Rabbit IgG |
Antigen Source | HUMAN |
Gene ID | 10963 |
---|---|
Antigen Region | 269-297 aa |
Other Names | STIP1; Stress-induced-phosphoprotein 1; Hsc70/Hsp90-organizing protein; Renal carcinoma antigen NY-REN-11; Transformation-sensitive protein IEF SSP 3521 |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Target/Specificity | This STIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-297 amino acids from the Central region of human STIP1. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | STIP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STIP1 (HGNC:11387) |
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Function | Acts as a co-chaperone for HSP90AA1 (PubMed:27353360). Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90 (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q60864}. Nucleus {ECO:0000250|UniProtKB:Q60864}. Dynein axonemal particle {ECO:0000250|UniProtKB:Q7ZWU1} |
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Provided below are standard protocols that you may find useful for product applications.
Background
STIP1 mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).
References
Onuoha,S.C., J. Mol. Biol. 379 (4), 732-744 (2008) Erlich,R.B., Glia 55 (16), 1690-1698 (2007)
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