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NDUFS7 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O75251 |
| Other Accession | Q9DC70, P42026 |
| Reactivity | Human, Mouse |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=24;M=25 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 374291 |
|---|---|
| Antigen Region | 119-146 aa |
| Other Names | NDUFS7;NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Complex I-20kD; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; NADH-ubiquinone oxidoreductase 20 kDa subunit; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; PSST subunit |
| Dilution | WB~~1:1000 |
| Target/Specificity | This NDUFS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-146 amino acids from the Central region of human NDUFS7. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NDUFS7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NDUFS7 |
|---|---|
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:17275378). Essential for the catalytic activity of complex I (PubMed:17275378). |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:P42026}; Matrix side {ECO:0000250|UniProtKB:P42026} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
References
Hyslop S.J., et al. Genomics 37:375-380(1996).
Grimwood J., et al. Nature 428:529-535(2004).
Murray J., et al. J. Biol. Chem. 278:13619-13622(2003).
Burkard T.R., et al. BMC Syst. Biol. 5:17-17(2011).
Triepels R.H., et al. Ann. Neurol. 45:787-790(1999).
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