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TPT1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P13693 |
| Other Accession | P61288, NP_003286.1 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | H=20,M=19,Rat=19 KDa |
| Isotype | Rabbit IgG |
| Antigen Source | HUMAN |
| Gene ID | 7178 |
|---|---|
| Antigen Region | 1-30 aa |
| Other Names | TPT1; Translationally-controlled tumor protein; Fortilin; Histamine-releasing factor; p23 |
| Dilution | WB~~1:1000 |
| Target/Specificity | This TPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TPT1. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TPT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TPT1 |
|---|---|
| Function | Involved in calcium binding and microtubule stabilization (PubMed:12167714, PubMed:15162379, PubMed:15958728). Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein (PubMed:18325344). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TPT1 is involved in calcium binding and microtubule stabilization.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Rid, R., et al. J. Steroid Biochem. Mol. Biol. 118 (1-2), 29-40 (2010) :
Ma, Q., et al. J. Proteome Res. 9(1):40-49(2010)
Dong, X., et al. J. Biol. Chem. 284(35):23754-23764(2009)
Wu, P.S., et al. J. Immunol. 183(4):2373-2381(2009)
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