PITPNA Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q00169 |
Other Accession | P16446, P48738, P53810, Q2HJ54 |
Reactivity | Human, Mouse, Rat |
Predicted | Bovine, Rabbit |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | H=32;M=32;Rat=32 KDa |
Isotype | Rabbit IgG |
Antigen Source | Human |
Gene ID | 5306 |
---|---|
Antigen Region | 243-270 aa |
Other Names | Phosphatidylinositol transfer protein alpha isoform;PITPN; Phosphatidylinositol transfer protein alpha isoform |
Dilution | WB~~1:2000 IHC-P~~1:25 |
Target/Specificity | This PITPNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-270 amino acids from the C-terminal region of human PITPNA. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PITPNA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PITPNA |
---|---|
Synonyms | PITPN |
Function | Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:10531358, PubMed:14962392, PubMed:15522822, PubMed:18636990, PubMed:22822086). Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (PubMed:15522822, PubMed:22822086). Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 (PubMed:22822086). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P53810}. Nucleus {ECO:0000250|UniProtKB:P53810} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
References
Dickeson S.K., et al. Gene 142:301-305(1994).
Tanaka S., et al. Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
Lubec G., et al. Submitted (MAR-2007) to UniProtKB.
Rikova K., et al. Cell 131:1190-1203(2007).
Choudhary C., et al. Science 325:834-840(2009).
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