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MMAB Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - MMAB Antibody (Center) AW5050-U100
    Western blot analysis of lysates from A431, Hela cell line, human liver tissue, HepG2 cell line and human skeletal muscle tissue lysate (from left to right),using MMAB Antibody (Center)(Cat. #AW5050). AW5050 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q96EY8
Other Accession Q9D273
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW H=27;M=26,28 KDa
Isotype Rabbit IgG
Antigen Source HUMAN
Additional Information
Gene ID 326625
Antigen Region 50-81 aa
Other Names Cob(I)yrinic acid a, c-diamide adenosyltransferase, mitochondrial, Cob(I)alamin adenosyltransferase, Methylmalonic aciduria type B protein, MMAB
Dilution WB~~1:1000
Target/Specificity This MMAB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 50-81 amino acids from the Central region of human MMAB.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMMAB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMAB (HGNC:19331)
Function Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion (PubMed:12514191). Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP- binding to MMAB and gated by MMAA (Probable).
Cellular Location Mitochondrion.
Tissue Location Expressed in liver and skeletal muscle.
Research Areas
Citations (0)
citation

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References

Dobson C.M.,et al.Hum. Mol. Genet. 11:3361-3369(2002).
Leal N.A.,et al.J. Biol. Chem. 278:9227-9234(2003).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Schubert H.L.,et al.Biochemistry 45:15188-15196(2006).
Martinez M.A.,et al.Mol. Genet. Metab. 84:317-325(2005).

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$ 370.00
Cat# AW5050-U100
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