Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
FITC Anti-Human CD5 (L17F12) Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC |
|---|---|
| Isotype | Mouse IgG2a, kappa |
| Concentration | 5 µL (0.125 µg)/test |
| Reactivity | Human |
| Formulation | 10mM NaH2PO4, 150 mM NaCl, 0.09% NaN3,0.1%gelatin,pH7.2 0.1% gelatin, pH7.2 |
| Gene ID | 921 |
|---|---|
| Gene Name | CD5 |
| Alternative Name(s) | Leu-1, T1 |
| Format | FITC |
| Storage Conditions | 2-8°C protected from light |
Provided below are standard protocols that you may find useful for product applications.
Background
The L17F12 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is a member of the scavenger receptor superfamily and is present on approximately 70% of normal peripheral blood lymphocytes. CD5 is involved in modulating antigen receptor signaling in both T and B cells and acts through binding of CD72, its receptor expressed on B cells.
References
Knapp W, Dorken B, et al. eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York.
Gadol N and Ault KA. 1986. Immunol Rev. 93: 23-34.
Antin JH, Emerson SG, Martin P, Gadol N and Ault KA. 1986. J Immunol. 136: 505-510.
Raab M, Yamamoto M and Rudd CE. 1994. Mol Cell Biol. 14(5): 2862-2870.
Lydyard PM, Lamour A, MacKenzie LE, Jamin C, Magged RA and Youinou P. 1993. Immunol Lett. 38(2): 159-166.
McKenna RW, Washington LT, Aquino DB, Picker LJ and Kroft SH. 2001. Blood. 98(8): 2498-2507. (Flow Cytometry)
Butmarc JR, Kourea HP, Levi E and Kadin ME. 1998. Am J Clin Path. 109(6): 682-688. (Immunohistochemistry - paraffin-embedded tissue)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
